Alzheimer's prevention: Does it exist? (2024)

Are there any proven Alzheimer's prevention strategies?

Answer From Jonathan Graff-Radford, M.D.

Not yet. But there's strong evidence that healthy lifestyle habits — such as diet, exercise and not smoking — may play a role in reducing your risk of Alzheimer's disease and other types of dementia. However, more research is needed before any of these lifestyle factors can be considered a proven strategy to prevent Alzheimer's disease.

In particular, the Mediterranean diet has been associated with a reduced risk of Alzheimer's disease and dementia. The Mediterranean diet is also linked to improved cognition in people who are at risk of heart and other vascular diseases.

The Mediterranean diet is rich in fruits, vegetables, legumes, whole grains and fish and uses olive oil as the primary cooking fat. This type of diet is also a heart-healthy diet that reduces the risk of conditions such as high blood pressure, high cholesterol and type 2 diabetes. These conditions are also risk factors for dementia.

More research is needed before experts know specific ways to prevent Alzheimer's. But here are some steps that promote good overall brain health:

  • Avoid smoking.
  • Control vascular risk factors, including high blood pressure, high cholesterol and diabetes.
  • Eat a balanced diet — such as the Mediterranean diet — that's rich in vegetables, fruits and lean protein, particularly protein sources containing omega-3 fatty acids.
  • Be physically and socially active, including engaging in aerobic exercise.
  • Maintain a healthy weight.
  • Take care of your mental health.
  • Use thinking (cognitive) skills, such as memory skills.
  • Avoid head injury.
  • Treat hearing loss.
  • Limit alcohol consumption.

March 13, 2024

  1. NIH consensus development conference statement on preventing Alzheimer's disease and cognitive decline. NIH Consensus and State-of-the-Science Statements. 2010;27:1.
  2. Press D, et al. Prevention of dementia. https://www.uptodate.com/contents/search. Accessed March 31, 2022.
  3. Duplantier SC, et al. A critical review of the study of neuroprotective diets to reduce cognitive decline. Nutrients. 2021; doi:10.3390/nu13072264.
  4. Can Alzheimer's disease be prevented? Alzheimer's Association. https://www.alz.org/alzheimers-dementia/research_progress/prevention. Accessed March 31, 2022.
  5. Guzman-Martinez L, et al. New frontiers in the prevention, diagnosis and treatment of Alzheimer's disease. Journal of Alzheimer's disease. 2021; doi:10.3233/JAD-201059.
  6. Livingston G, et al. Dementia prevention, intervention, and care: 2020 report of the Lancet Commission. Lancet Commissions. doi:10.1016/S0140-6736(20)30367-6.
  7. Graff-Radford J (expert opinion). Mayo Clinic; March 31, 2022.

See more Expert Answers

See also

  1. Alzheimer's sleep problems
  2. Alzheimer's: New treatments
  3. Alzheimer's 101
  4. Understanding the difference between dementia types
  5. Alzheimer's disease
  6. Alzheimer's genes
  7. Alzheimer's drugs
  8. Alzheimer's stages
  9. Antidepressant withdrawal: Is there such a thing?
  10. Antidepressants and alcohol: What's the concern?
  11. Antidepressants and weight gain: What causes it?
  12. Antidepressants: Can they stop working?
  13. Antidepressants: Side effects
  14. Antidepressants: Selecting one that's right for you
  15. Antidepressants: Which cause the fewest sexual side effects?
  16. Anxiety disorders
  17. Atypical antidepressants
  18. Caregiver stress
  19. Clinical depression: What does that mean?
  20. Corticobasal degeneration (corticobasal syndrome)
  21. CT scan
  22. Depression and anxiety: Can I have both?
  23. Depression, anxiety and exercise
  24. What is depression? A Mayo Clinic expert explains.
  25. Depression in women: Understanding the gender gap
  26. Depression (major depressive disorder)
  27. Depression: Supporting a family member or friend
  28. Diagnosing Alzheimer's
  29. Did the definition of Alzheimer's disease change?
  30. How your brain works
  31. Intermittent fasting
  32. Lecanemab for Alzheimer's disease
  33. Male depression: Understanding the issues
  34. MAOIs and diet: Is it necessary to restrict tyramine?
  35. Marijuana and depression
  36. Mayo Clinic Minute: 3 tips to reduce your risk of Alzheimer's disease
  37. Mayo Clinic Minute: Alzheimer's disease risk and lifestyle
  38. Mayo Clinic Minute: New definition of Alzheimer's changes
  39. Mayo Clinic Minute: Women and Alzheimer's Disease
  40. Memory loss: When to seek help
  41. Monoamine oxidase inhibitors (MAOIs)
  42. MRI
  43. Natural remedies for depression: Are they effective?
  44. Nervous breakdown: What does it mean?
  45. New Alzheimers Research
  46. Pain and depression: Is there a link?
  47. Phantosmia: What causes olfactory hallucinations?
  48. Positron emission tomography scan
  49. Posterior cortical atrophy
  50. Seeing inside the heart with MRI
  51. Selective serotonin reuptake inhibitors (SSRIs)
  52. Serotonin and norepinephrine reuptake inhibitors (SNRIs)
  53. Sundowning: Late-day confusion
  54. Treatment-resistant depression
  55. Tricyclic antidepressants and tetracyclic antidepressants
  56. Video: Alzheimer's drug shows early promise
  57. MRI
  58. Vitamin B-12 and depression
  59. Young-onset Alzheimer's

.

Alzheimer's prevention: Does it exist? (2024)

FAQs

Could Alzheimer's have been prevented? ›

As the exact cause of Alzheimer's disease is still unknown, there's no certain way to prevent the condition.

Is the Alzheimer's organization legitimate? ›

Formed in 1980, the Alzheimer's Association is the leading voluntary health organization in Alzheimer's care, support and research.

Is Alzheimer's Curable or Preventable? ›

There's no cure for Alzheimer's, but there are treatments that may change disease progression, and drug and non-drug options that may help treat symptoms. Understanding available options can help individuals living with the disease and their caregivers to cope with symptoms and improve quality of life.

Are we close to finding a cure for Alzheimer's? ›

And, while there are a number of therapeutic treatments available to people with the disease, there's currently no cure. Will there ever be? That's the question a number of researchers at Boston University are tackling, and with vastly different approaches.

Why is Alzheimer's so common now? ›

Increasing age is the greatest known risk factor for Alzheimer's disease. Alzheimer's isn't a part of typical aging. But as you grow older, the chances of developing it increases. One study found that every year there were four new diagnoses per 1,000 people ages 65 to 74.

What is the #1 preventable cause of Alzheimer's? ›

Controlling high blood pressure is known to reduce a person's risk for heart disease and stroke, and it also might help prevent or delay Alzheimer's. High blood pressure, particularly in midlife, is considered a risk factor for later-life cognitive decline.

What are three causes of Alzheimer's? ›

The causes probably include a combination of age-related changes in the brain, along with genetic, environmental, and lifestyle factors. The importance of any one of these factors in increasing or decreasing the risk of developing Alzheimer's may differ from person to person.

What deficiency causes Alzheimer's disease? ›

Levels of one neurotransmitter, acetylcholine, are particularly low in the brains of people with Alzheimer's disease. Over time, different areas of the brain shrink.

What is the salary of the CEO of Alzheimer's Association? ›

Nonprofit Compensation Packages of $1 Million or More
Name & TitleCharityCompensation
Note: Includes $1,005,253 defined benefit supplemental executive retirement plan payment.
James R. Downing, M.D. President/CEOSt. Jude Children's Research Hospital$1,546,372
Harry Johns Past President/CEOAlzheimer's Association$1,481,516
49 more rows

What is the number one food that fights dementia? ›

There's no single or “best” food to fight dementia. Eating patterns that include several anti-inflammatory foods may help to prevent or slow dementia. These include leafy greens, nuts, berries, whole grains, beans, and olive oil.

What are three foods that prevent Alzheimer's? ›

Many foods — blueberries, leafy greens, and curcumin (found in the spice turmeric), to name a few — have been studied for their potential cognitive benefit. These foods have been thought to have anti-inflammatory, antioxidant, or other properties that might help protect the brain.

What is the number one way to prevent Alzheimer's? ›

Avoid smoking. Control vascular risk factors, including high blood pressure, high cholesterol and diabetes. Eat a balanced diet — such as the Mediterranean diet — that's rich in vegetables, fruits and lean protein, particularly protein sources containing omega-3 fatty acids.

What hormone prevents Alzheimer's? ›

Their tests have shown that leptin can reduce the effects of two toxic proteins in the brain called amyloid and tau, which build up and lead to memory loss and development of Alzheimer's disease.

Why have we failed to cure Alzheimer's disease? ›

Part of the problem comes back to the lack of clarity on the cause of Alzheimer's and the steep costs of developing a single drug. Ballard says it's also a problem that there's less awareness around dementia — and less hope.

How close are we to stopping dementia? ›

There is currently no cure for dementia. In fact, because dementia is caused by different diseases it is unlikely that there will be a single cure for dementia. Research is aimed at finding cures for dementia-causing diseases, such as Alzheimer's disease, frontotemporal dementia and dementia with Lewy bodies.

Could Alzheimer's ever be cured? ›

There are currently no known interventions that will cure Alzheimer's.

Can Alzheimer's be prevented or reversed? ›

There are currently no approaches that have been proven to prevent Alzheimer's disease and related dementias. However, as with many other diseases, there may be steps you can take to help reduce your risk.

How can Alzheimer's be prevented early in life? ›

How You Can Reduce Your Risk of Alzheimer's
  1. Prevent and manage high blood pressure. ...
  2. Manage blood sugar. ...
  3. Maintain a healthy weight. ...
  4. Be physically active. ...
  5. Quit smoking. ...
  6. Avoid excessive drinking. ...
  7. Prevent and correct hearing loss. ...
  8. Get enough sleep.

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