About this Guide
Updated for patch 7.22, but without runes. My guess is that Comet is the best keystone, as I have seen a challenger player take it on MF support, but that's just a guess for now, as I don't have the full data available.
Check the notes on the items for more details on the items.
I created this guide by crafting a build from the item win rate data over at lolalytics.com for Miss Fortune on ARAM. In game, I use the Example Build as a guideline and use the items by win rate section to inform my decision making for alternate builds.
Don't get stuck building just one way because it is the highest win rate way. Build what will help your team the most! This guide is just for information and if you are not sure what to build.